Life on Mounjaro: Weeks 2 and 3

Today marked my 4th injection of Mounjaro 2.5 milligrams. Weeks 2 and 3 have been an adventure of sorts. After experiencing some side effects and weight loss in week 1, the side effects caused by the injections have lessened and evened out a bit. The weight loss also stopped for a few days. I didn’t gain in week 2, but I didn’t lose much either. As I moved into Week 3 though, the weight seems to have begun dropping again. As of yesterday I was at a total loss of 8.5 lbs, but my official weigh in day isn’t until Monday.

My Diet

The appetite suppression is remaining and I am doing my best to lean into that a bit. I see some people in discussion forums who say the appetite suppression comes and goes a bit, but that hasn’t been my experience. I seem to have settled in at consuming around 1100 calories per day. I’ve been focusing on a low sugar diet due to my diabetes and am basically eating keto without really putting much thought into it. Since I’ve started Mounjaro, only some foods are appealing to me. Mostly, these are bland foods that are lower in sugar. Chicken, nuts, cheeses, and protein shakes. I have also been eating some naan bread which is delicious and low in sugar … its not keto, but a half slice makes for a good chicken or salmon sandwich!

The biggest impact the Mounjaro has had on my diet is that it has taken away my desire to eat sweets or junk food. The food “chatter” that used to cloud my brain seems to have dissipated. This has allowed me to follow my diet consistently with no “cheat” days or lapses in judgement. Honestly, I feel as if this is the edge I have always been lacking.

The Community

Over the last two weeks I learned there is a thriving community of “mounjarians” who are sharing their experience and advice. On YouTube alone there are some fantastic resources. Two of the channels I find the most informative and enjoyable are BJ Davis and the Man on the Mounjaro’s Dave Knapp. I find it helpful to see how other men have adjusted to life on Mounjaro. One example from the week was when BJ Davis shared via his channel that the pain medication “meloxicam” had stalled his weight loss. I have taken meloxicam for some time for my arthritis and had never realized weight gain and water retention was a side effect. A quick google search supported what BJ had said so I am now trying to manage my arthritis without the meloxicam. I am interested in seeing if this experiment impacts my weight loss in any way … if not, I can always start taking the pain meds again, At the moment though, I’m willing to work through a little bit more pain in favor of weight loss, which will favorable impact my arthritis as well. At any rate, this is something I wouldn’t have learned at it not been for BJ’s video, and for that, I am grateful. BJ also hosts a Discord channel which is chock full of good information and discussion.

Moving Forward

I have one week left on 2.5 and will move up to 5.0 milligrams of Mounjaro for the next two months after that. I am looking forward to continuing this journey and will continue to journal my experience here for any who may find it helpful. So far, I haven’t been impacted by any of the supply chain issues that others have suffered through, and I pray my luck continues to hold out!

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The Mounjaro Effect: Side-Effects I didn’t Quite Expect

I have been Mounjaro for about a week and a half. I was well prepared for some of the side effects such as stomach distress and appetite loss, however, there have some other effects I didn’t expect. First, my tolerance for water has dramatically increased – I would dare say I even like it. I’ve been sipping on water almost constantly since starting Mounjaro which is weird because I’ve never enjoyed plain, clear H2O. My beverage of choice has always been Diet Pop/Soda. Oddly enough, as my desire for water has increased, my thirst for all things diet has decreased. I’ve still had some, but not nearly as much as I consumed pre-injection. I’ve also been able to get in my daily quota of coffee!

My food tastes have also changed just a bit. As my appetite has been largely suppressed, the only foods that have really appealed to me are bland ones. Nuts, mild cheeses, chicken breasts, and naan bread have been the only things that I’ve actually wanted. I ate some salmon on a half slice of naan bread and felt like I was eating something truly exquisite. I haven’t had an urge to snack on sweets, chips, or fried foods since my first injection. This is itself is a blessing.

And while it’s too early for me to tell if this is related to the Mounjaro, I have been sleeping through the night for the first time in a long time … not even waking up to use the restroom. Normally, it takes a shot of Nyquil for me to enjoy some rest, but for three nights strait, I’ve gotten more than eight hours. Maybe it’s coincidence, but Mounjaro and diet are the only things I’ve really changed.

Finally, I’ve seen some people comment that Mounjaro has robbed them of their energy … and I have certainly felt a little tired for the last week or so. The good news is that I’ve still been able to run and get my exercise in.

These are some of the changes I’ve noticed since starting Mounjaro. I can’t help but wonder if they will persist or fade as I progress. I suppose time will tell! ou

Life on Mounjaro: Week 1

I have documented my weight loss and health pursuits in great detail (including Season 1 of the Dying2Self Podcast) so I will not recap my entire history here, however, as a means of context please indulge me for just a bit. I was diagnosed with Type 2 Diabetes at 368 lbs. This was not my heaviest weight. Unfortunately, my weight has bounced around throughout my adult life with a high of 390+ and a low of 178 lbs. After being diagnosed with diabetes, I made health a priority and developed a love (and hate) for long distance running. I even lost a great deal of weight by means of white-knuckled determination, however, my weight always seems to plateau around the 275 pound mark. Desperate to bust this plateau to help my running, I went out on a limb and went all in on a plan known as Optavia a couple years ago … and I enjoyed great success as I even dropped below 200 lbs briefly. I’ll write more about Optavia and my thoughts about it at some point as, honestly, I’m still trying to sort it out in my mind … but suffice it to say that after stopping the program my weight immediately shot back up to 275 lbs where it remained steady despite my best efforts.

When I learned recently I had a destroyed meniscus in my left knee and a diagnosis of bone on bone arthritis in the same knee, I knew weight loss had to be a priority if I wanted to continue running at all. Life as a clydesdale runner is tough enough, but with a bad knee, it’s near impossible. As I discussed this with my physician, she mentioned Mounjaro. This is a weekly injectable medication I qualified for due to my Type 2 Diabetes diagnosis. In addition to lowering my a1c, blood pressure, and protecting against other downsides of diabetes, Mounjaro would also help me lose weight and bust through that plateau. I’m not a big fan of medications, but in desperation, I decided to give it a shot. There was the possibility of some negative side-effects, but after weighing them and praying about it, I felt it was worth it to give Mounjaro a try. I won’t go into detail here at all about how this medication works as there is a bunch of information about it online. Just google GLP-1 weight loss or Mounjaro and you’ll be able to read all about it.

I know that Mounjaro and similar medications like Ozempic and Wegovy are all the rage right now and are getting a lot of media attention. So my goal with the “Life on Mounjaro” series will be to chronicle my experience on the medication. I’m not a doctor, and I’m not making any recommendations, I’m simply chronicling my experience for those who are interested in this class of medications.

Life on Mounjaro: Week 1

I picked up my prescription for the introductory dosage of Mounjaro on Monday, 2/20/23. In my excited, I took my first dose that evening around 8:00 pm. In retrospect, this was a mistake. I’ll explain why here in a bit. I didn’t notice much of an effect for the first few hours, however, on Tuesday when I woke up I realized I had virtually no appetite. Normally, I am constantly thinking about food. What am I gonna eat? When am I gonna eat? How much am I gonna eat? Those questions were not bouncing around in my brain any longer. I also didn’t notice much as far as side effects early on other than a weak stomach – not necessarily nausea – just a weak sensation. As the week progressed, my appetite remained suppressed and I developed a tad bit of acid reflux. It wasn’t anything that hurt or interfered with my day, in fact, I wasn’t even sure what it was until I read some Reddit forum members describing the same sensation. One of those people offered that a daily Prilosec ended the sensation so I ran out and grabbed some … it worked for me as well.

During the week I also began watching some YouTubers who chronicle their Mounjaro journey via that platform. On more than one occasion it was recommended that you take your injections at the beginning of the weekend. Why? In some cases, people stated the appetite suppression began to wear out as the injection day approached and taking the medication on Fridays or Saturdays helped curb weekend over indulging. Others suggested that gastric side effects of Mounjaro were normally more pronounced in the first 24 hours after an injection, so taking in on Friday or Saturday allowed them to weather the side effects before returning to work on Monday. Both reasons seemed valid to me, but I had already screwed up and taken my first injection on a Monday. A quick review of the guide that came with my prescription. however, revealed I could change my injection date provided 72 hours had passed since my last injection. With that in mind, I took my second dose of Mounjaro on Saturday morning – 5 days after my first injection. That’s when the side effects reared their ugly head!

After my second injection, I suffered from some pretty bad nausea. It kept me awake that first night as wave after wave of nausea crashed into me. I’n not sure if it was because I took the dose early or if my body was still acclimating to the medication, but it was a rough couple of hours for sure. Fortunately, it had all passed by morning and my nausea retreated back to the weak stomach sensation I am now growing used to. I am happy to report though that after seven days on Mounjaro, my appetite is still majorly suppressed and I am no longer obsessing over my next meal. If anything, I need to make it my goal in Week 2 to eat more as I realize I am not eating enough day to day as it is.

My weight loss for the week was 7.2 pounds and I am fairly ecstatic about that. It’s only been a week so I don’t want to make a bigger deal out of it than it is, but with my appetite suppressed, I feel confident I can overcome my weight plateau.

Tips I learned for the week?

If you are considering Mounjaro, prepare for the possible side effects. It may not be a bad idea to have some Prilosec and some Pepto on standby if needed. I didn’t have any Pepto in the house when my nausea hit which made it that much worse. Also, check out YouTube as there are tone of resources and testimonials concerning Mounjaro on that platform. I’ll post about some of the ones I enjoy at some point.

If you are diabetic and find yourself at a weight loss plateau, it might not be a bad idea to talk to your Doctor about Mounjaro. It could be exactly what you need. I for one am hopeful for the first time in awhile.

I’ll do my best to continue documenting my journey with Mounjaro and hope you will find it helpful.