I have documented my weight loss and health pursuits in great detail (including Season 1 of the Dying2Self Podcast) so I will not recap my entire history here, however, as a means of context please indulge me for just a bit. I was diagnosed with Type 2 Diabetes at 368 lbs. This was not my heaviest weight. Unfortunately, my weight has bounced around throughout my adult life with a high of 390+ and a low of 178 lbs. After being diagnosed with diabetes, I made health a priority and developed a love (and hate) for long distance running. I even lost a great deal of weight by means of white-knuckled determination, however, my weight always seems to plateau around the 275 pound mark. Desperate to bust this plateau to help my running, I went out on a limb and went all in on a plan known as Optavia a couple years ago … and I enjoyed great success as I even dropped below 200 lbs briefly. I’ll write more about Optavia and my thoughts about it at some point as, honestly, I’m still trying to sort it out in my mind … but suffice it to say that after stopping the program my weight immediately shot back up to 275 lbs where it remained steady despite my best efforts.
When I learned recently I had a destroyed meniscus in my left knee and a diagnosis of bone on bone arthritis in the same knee, I knew weight loss had to be a priority if I wanted to continue running at all. Life as a clydesdale runner is tough enough, but with a bad knee, it’s near impossible. As I discussed this with my physician, she mentioned Mounjaro. This is a weekly injectable medication I qualified for due to my Type 2 Diabetes diagnosis. In addition to lowering my a1c, blood pressure, and protecting against other downsides of diabetes, Mounjaro would also help me lose weight and bust through that plateau. I’m not a big fan of medications, but in desperation, I decided to give it a shot. There was the possibility of some negative side-effects, but after weighing them and praying about it, I felt it was worth it to give Mounjaro a try. I won’t go into detail here at all about how this medication works as there is a bunch of information about it online. Just google GLP-1 weight loss or Mounjaro and you’ll be able to read all about it.
I know that Mounjaro and similar medications like Ozempic and Wegovy are all the rage right now and are getting a lot of media attention. So my goal with the “Life on Mounjaro” series will be to chronicle my experience on the medication. I’m not a doctor, and I’m not making any recommendations, I’m simply chronicling my experience for those who are interested in this class of medications.
Life on Mounjaro: Week 1
I picked up my prescription for the introductory dosage of Mounjaro on Monday, 2/20/23. In my excited, I took my first dose that evening around 8:00 pm. In retrospect, this was a mistake. I’ll explain why here in a bit. I didn’t notice much of an effect for the first few hours, however, on Tuesday when I woke up I realized I had virtually no appetite. Normally, I am constantly thinking about food. What am I gonna eat? When am I gonna eat? How much am I gonna eat? Those questions were not bouncing around in my brain any longer. I also didn’t notice much as far as side effects early on other than a weak stomach – not necessarily nausea – just a weak sensation. As the week progressed, my appetite remained suppressed and I developed a tad bit of acid reflux. It wasn’t anything that hurt or interfered with my day, in fact, I wasn’t even sure what it was until I read some Reddit forum members describing the same sensation. One of those people offered that a daily Prilosec ended the sensation so I ran out and grabbed some … it worked for me as well.
During the week I also began watching some YouTubers who chronicle their Mounjaro journey via that platform. On more than one occasion it was recommended that you take your injections at the beginning of the weekend. Why? In some cases, people stated the appetite suppression began to wear out as the injection day approached and taking the medication on Fridays or Saturdays helped curb weekend over indulging. Others suggested that gastric side effects of Mounjaro were normally more pronounced in the first 24 hours after an injection, so taking in on Friday or Saturday allowed them to weather the side effects before returning to work on Monday. Both reasons seemed valid to me, but I had already screwed up and taken my first injection on a Monday. A quick review of the guide that came with my prescription. however, revealed I could change my injection date provided 72 hours had passed since my last injection. With that in mind, I took my second dose of Mounjaro on Saturday morning – 5 days after my first injection. That’s when the side effects reared their ugly head!
After my second injection, I suffered from some pretty bad nausea. It kept me awake that first night as wave after wave of nausea crashed into me. I’n not sure if it was because I took the dose early or if my body was still acclimating to the medication, but it was a rough couple of hours for sure. Fortunately, it had all passed by morning and my nausea retreated back to the weak stomach sensation I am now growing used to. I am happy to report though that after seven days on Mounjaro, my appetite is still majorly suppressed and I am no longer obsessing over my next meal. If anything, I need to make it my goal in Week 2 to eat more as I realize I am not eating enough day to day as it is.
My weight loss for the week was 7.2 pounds and I am fairly ecstatic about that. It’s only been a week so I don’t want to make a bigger deal out of it than it is, but with my appetite suppressed, I feel confident I can overcome my weight plateau.
Tips I learned for the week?
If you are considering Mounjaro, prepare for the possible side effects. It may not be a bad idea to have some Prilosec and some Pepto on standby if needed. I didn’t have any Pepto in the house when my nausea hit which made it that much worse. Also, check out YouTube as there are tone of resources and testimonials concerning Mounjaro on that platform. I’ll post about some of the ones I enjoy at some point.
If you are diabetic and find yourself at a weight loss plateau, it might not be a bad idea to talk to your Doctor about Mounjaro. It could be exactly what you need. I for one am hopeful for the first time in awhile.
I’ll do my best to continue documenting my journey with Mounjaro and hope you will find it helpful.